Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11997023 | 0.96 | — | — | |
| Bromide SCHEMBL9737932 | 0.82 | MAOA (0.41) | — | |
| SCHEMBL17624446 | 0.77 | MAOA (0.42) | — | |
| SCHEMBL25774454 | 0.77 | — | — | |
| SCHEMBL19498042 | 0.75 | — | — | |
| SCHEMBL16456474 | 0.75 | CHRNA7 (0.30) | — | |
| SCHEMBL26789407 | 0.75 | — | — | |
| SCHEMBL26790520 | 0.75 | — | — | |
| SCHEMBL14964062 | 0.74 | — | — | |
| SCHEMBL26849759 | 0.73 | SIGMAR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089621-A | Intermediates for cephalosporins or quinolone derivative antibiotics | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-02-18 | — | — | US | disclosed |
| EP-0424852-A1 | Diazabicycloamine compounds and a process for their preparation | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-05-02 | — | — | EP | disclosed |