Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11701928 | 0.96 | BRD4 (0.43) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL9633492 | 0.92 | SMN1; SMN2 (0.46) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL8408089 | 0.88 | TP53 (0.44) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL8410901 | 0.88 | TP53 (0.44) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL8410904 | 0.88 | TP53 (0.44) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL8408087 | 0.88 | TP53 (0.44) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL17014460 | 0.87 | BRD4 (0.47) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL4868550 | 0.87 | BRD4 (0.47) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL1139285 | 0.87 | BRD4 (0.47) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL13245966 | 0.83 | BRD4 (0.38) | BRD4TP53SMN1; SMN2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865889-A | Synthesis method of benzisoquinoline compound | 山东省药学科学院 | 2024-04-12 | — | — | CN | claimed |
| CN-114426497-A | Preparation method of trans-4-aminocyclohexanecarboxylic acid hydrochloride | 泰州精英化成医药科技有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-109678788-B | 1, 2-diaryl indole, derivative and synthetic method thereof | 湘潭大学 | 2021-05-04 | — | — | CN | claimed |
| CN-109678788-A | A kind of 1,2- diaryl indoles, derivative and its synthetic method | 湘潭大学 | 2019-04-26 | — | — | CN | claimed |
| CN-105001296-B | A kind of nitric oxide donator type dexamethasone and preparation method and purposes | 中国人民解放军第三军医大学 | 2016-11-30 | — | — | CN | claimed |
| EP-0257727-B1 | PROCESS FOR PREPARING CYCLOHEXANONECARBOXYLIC ACID COMPOUNDS | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-08-30 | — | — | EP | claimed |
| US-4785132-A | CATALYTIC HYDROGENATION OF HYDROXYBENZOIC ACIDS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1988-11-15 | — | — | US | claimed |
| EP-0257727-A1 | Process for preparing cyclohexanonecarboxylic acid compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-03-02 | — | — | EP | claimed |
| US-12583839-B2 | PD-L1 antagonist compound | ADLAI NORTYE BIOPHARMA CO., LTD. (CN) | 2026-03-24 | — | — | US | disclosed |
| EP-4121421-B1 | BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS | NOVARTIS AG (CH) | 2026-03-11 | — | — | EP | disclosed |
| US-20250388593-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2025-12-25 | — | — | US | disclosed |
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | Jubilant Epicore LLC (US) | 2025-11-25 | — | — | US | disclosed |
| EP-4650348-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2025-11-19 | — | — | EP | disclosed |
| EP-3455204-B1 | CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS | Jubilant Epicore LLC (US) | 2025-10-29 | — | — | EP | disclosed |
| US-4629805-A | Alkyl substituted and unsubstituted para-carboalkoxy cyclohexanones and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4614831-A | FROM PHENOL DERIVATIVES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-09-30 | — | — | US | disclosed |
| US-4537704-A | Alkyl substituted and unsubstituted para-carboalkoxy cyclohexanones and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-08-27 | — | — | US | disclosed |
| US-4370323-A | 2-Cyanoaziridinyl-(1)-2-substituted-aziridinyl-(1)-methanes | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| US-3953425-A | Azepine indanyl and tetralin butyrophenones | THE UPJOHN COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
| US-3948939-A | 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids | STERLING DRUG INC. (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479797-B2 | Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors | HDAC1, HDAC11, HDAC2 | BRD4 362/4885TP53 440/4885SMN1; SMN2 1068/4885 |
| US-20250388593-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | CRBN, CUL1, CBL | BRD4 1339/4885TP53 1819/4885SMN1; SMN2 566/4885 |
| US-12583839-B2 | PD-L1 antagonist compound | CD274, PDCD1LG2, PDCD1 | BRD4 842/4885TP53 927/4885SMN1; SMN2 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.