SCHEMBL7912342

SCHEMBL7912342

Oc1nc(-c2ccccc2)cnc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
PDGFRB P09619 1/20 0.44
KDR P35968 1/20 0.44
FLT3 P36888 1/20 0.44
MAPK1 P28482 2/20 0.43
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
TLR9 Q9NR96 1/20 0.42
CKS1B P61024 1/20 0.42
SKP1 P63208 1/20 0.42
SKP2 Q13309 1/20 0.42
ATR Q13535 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28283875 0.84 BCHE (0.46) BCHESMN1; SMN2RAB9ANPC1PDGFRB
SCHEMBL7567737 0.82 CKS1B (0.43) SMN1; SMN2CKS1BSKP1SKP2MEN1
SCHEMBL87574 0.81 CKS1B (0.55) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL27328541 0.79 KMT2A (0.59) BCHEMAPK1CKS1BSKP1SKP2
SCHEMBL29406280 0.79 CKS1B (0.53) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL28243355 0.79 CKS1B (0.53) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL27816089 0.79 CKS1B (0.53) SMN1; SMN2RAB9ANPC1PDGFRBKDR
SCHEMBL11218540 0.78 JAK3 (0.45) SMN1; SMN2RAB9ACKS1BSKP1SKP2
SCHEMBL16750246 0.78 CKS1B (0.52) BCHESMN1; SMN2RAB9ANPC1PDGFRB
SCHEMBL28438494 0.76 KDM4E (0.52) SMN1; SMN2RAB9ANPC1PDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed