Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30478423 | 0.85 | CKS1B (0.53) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL2036410 | 0.85 | CKS1B (0.53) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL7912342 | 0.82 | BCHE (0.46) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL11218540 | 0.80 | JAK3 (0.45) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL15135221 | 0.75 | MEN1 (0.50) | MEN1KMT2AADORA2AADORA1KDM4E | |
| SCHEMBL11224246 | 0.72 | ADORA1 (0.40) | CKS1BSKP1SKP2MEN1KMT2A | |
| SCHEMBL8895956 | 0.71 | SLC22A12 (0.43) | MEN1KMT2AADORA2AADORA1KDM4E | |
| SCHEMBL3593759 | 0.70 | KMT2A (0.67) | MEN1KMT2AKDM4EPKML3MBTL1 | |
| SCHEMBL28283875 | 0.69 | BCHE (0.46) | MEN1KMT2AKDM4EPKMMAPT | |
| SCHEMBL31039852 | 0.68 | CKS1B (0.53) | CKS1BSKP1SKP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002089809-A1 | MEDICINAL USES OF HYDRAZONES AND HYDRAZINES | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |