SCHEMBL7912353

SCHEMBL7912353

ClC(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
SLC6A4 P31645 1/20 0.49
CYP2A6 P11509 2/20 0.41
TSHR P16473 2/20 0.41
ACP3 P15309 2/20 0.40
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38
ADRA1B P35368 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30575787 1.00 ALDH1A1 (0.52) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL12880576 0.94 ALDH1A1 (0.54) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL30575775 0.86 CYP2C19 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL14033462 0.86 CYP2C19 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL30575789 0.85 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL29083663 0.85 ALDH1A1 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL4457608 0.81 KMT2A (0.48) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL5012390 0.78 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL40516 0.78 ALDH1A1 (0.56) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL6795411 0.78 SLC6A4 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836062-A Efficient preparation method of N, N-dimethyl-1-naphthylamine compound 大连理工大学 2023-10-03 CN disclosed
CN-113773206-B Preparation method of carbon dioxide-participated butenafine 山西大学 2022-05-31 CN disclosed
CN-113773206-A Preparation method of carbon dioxide-participated butenafine 山西大学 2021-12-10 CN disclosed
CN-111848467-B Preparation method of asymmetric organic persulfate compound 浙江大学 2021-07-20 CN disclosed
CN-111848467-A Preparation method of asymmetric organic persulfate compound 浙江大学 2020-10-30 CN disclosed
CN-106478387-B A kind of preparation method of the two arone compound containing Alpha-Naphthyl 大连理工大学 2019-02-01 CN disclosed
CN-106478387-A A kind of preparation method of naphthyl containing α two arone compound 大连理工大学 2017-03-08 CN disclosed
CN-105130823-B A kind of method of synthesis butenafine 中国科学技术大学 2017-03-01 CN disclosed
CN-105130823-A Butenafine synthesis method USTC UNIV SCIENCE TECH CN 2015-12-09 CN disclosed
CN-104370715-B A kind of synthetic method of alpha-aromatic ketone compound DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2015-10-28 CN disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1055367-A Ethene gas phase (being total to) polymeric carrier model polyolefin catalyst BP CHEM INT LTD (GB) 1991-10-16 CN disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed