SCHEMBL7912388

SCHEMBL7912388

c1ccc2nc3c(nc2c1)c1ccccc1c1nc2ccccc2nc13

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
MYC P01106 1/20 0.56
MAX P61244 1/20 0.56
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 4/20 0.52
HSD17B10 Q99714 4/20 0.52
GAA P10253 2/20 0.52
HPGD P15428 2/20 0.52
CASP1 P29466 4/20 0.50
CASP7 P55210 4/20 0.50
RAB9A P51151 4/20 0.50
MAPK10 P53779 3/20 0.50
NPC1 O15118 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 2/20 0.50
POLB P06746 1/20 0.50
GPR3 P46089 2/20 0.48
NQO2 P16083 3/20 0.46
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18805402 0.95 MYC (0.52) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL732274 0.94 MAPT (0.56) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL29581869 0.94 MAPT (0.56) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL10603701 0.92 MYC (0.54) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL29402115 0.87 MAPT (0.71) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL2246928 0.87 MAPT (0.71) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL29581806 0.87 MAPT (0.71) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL19445500 0.85 GPR3 (0.58) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL13156555 0.85 MYC (0.59) MAPTMYCMAXALDH1A1KDM4E
SCHEMBL10025827 0.85 HPRT1 (0.59) MAPTMYCMAXALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
US-6096144-A TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-01 US disclosed
US-5858571-A TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-01-12 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed