Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 7/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14828364 | 0.92 | PDE9A (0.44) | PDE9APDE5APDE1BSPRENPP2 | |
| SCHEMBL12044995 | 0.92 | PDE9A (0.45) | PDE9APDE5APDE1BSPRENPP2 | |
| SCHEMBL7899394 | 0.91 | PDE9A (0.47) | PDE9APDE5APDE1BSPRENPP2 | |
| SCHEMBL12045005 | 0.91 | PDE9A (0.43) | PDE9APDE5APDE1BSPRENPP2 | |
| SCHEMBL7908379 | 0.91 | PDE9A (0.43) | PDE9APDE5APDE1BSPR | |
| SCHEMBL7896928 | 0.91 | PDE9A (0.45) | PDE9APDE5ASPR | |
| SCHEMBL7908777 | 0.90 | PDE9A (0.45) | PDE9APDE5APDE1BSPR | |
| SCHEMBL14828367 | 0.89 | PDE9A (0.44) | PDE9APDE5APDE1BENPP2 | |
| SCHEMBL12044150 | 0.89 | SPR (0.46) | PDE9APDE5ASPR | |
| SCHEMBL7912364 | 0.89 | SPR (0.46) | PDE9APDE5ASPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101230-A1 | QUINOXALINE COMPOUNDS | アステラス製薬株式会社 (JP) | 2010-09-10 | — | — | WO | disclosed |