Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911276 | 0.87 | GAA (0.64) | GAANLRP3MEN1KMT2ARAB9A | |
| SCHEMBL7911338 | 0.85 | GAA (0.63) | GAANLRP3MEN1KMT2ARAB9A | |
| SCHEMBL7914152 | 0.85 | GAA (0.46) | GAANLRP3MEN1KMT2ARAB9A | |
| SCHEMBL7343997 | 0.83 | GAA (0.63) | GAANLRP3MEN1KMT2ARAB9A | |
| SCHEMBL11408239 | 0.81 | GAA (0.65) | GAAMEN1KMT2ARAB9ACA2 | |
| SCHEMBL131628 | 0.81 | GAA (0.65) | GAAMEN1KMT2ACA2CA1 | |
| SCHEMBL7144405 | 0.81 | GAA (0.65) | GAANLRP3MEN1KMT2ARAB9A | |
| SCHEMBL29598834 | 0.81 | GAA (0.65) | GAAMEN1KMT2ARAB9ACA2 | |
| SCHEMBL7257671 | 0.81 | GAA (0.64) | GAANLRP3MEN1KMT2ARAB9A | |
| SCHEMBL330293 | 0.80 | GAA (0.72) | GAANLRP3MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |