Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911330 | 0.86 | GAA (0.46) | GAAPOLBCA2IRAK4IDO1 | |
| SCHEMBL7912419 | 0.85 | GAA (0.63) | GAACA2NLRP3MEN1KMT2A | |
| SCHEMBL7914188 | 0.84 | GAA (0.48) | GAAPOLBCA2IRAK4MEN1 | |
| SCHEMBL7911352 | 0.77 | POLB (0.44) | GAAPOLBCA2MEN1KMT2A | |
| SCHEMBL7912402 | 0.76 | POLB (0.41) | GAAPOLBCA2CA4MEN1 | |
| SCHEMBL7917819 | 0.75 | CA1 (0.49) | GAAPOLBCA2CA4MEN1 | |
| SCHEMBL7914210 | 0.74 | CA2 (0.46) | GAACA2CA4MEN1KMT2A | |
| SCHEMBL21556096 | 0.73 | POLB (0.46) | GAAPOLBCA2CDK1CCNA2 | |
| SCHEMBL6112874 | 0.73 | POLB (0.64) | GAAPOLBCA2CA4MEN1 | |
| SCHEMBL3871603 | 0.71 | IRAK4 (0.55) | POLBIRAK4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |