Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 18/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317279 | 1.00 | MMP13 (0.79) | MMP13SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL1319136 | 0.89 | MMP13 (1.00) | MMP13 | |
| SCHEMBL1318244 | 0.83 | MMP13 (0.79) | MMP13 | |
| SCHEMBL1317326 | 0.82 | MMP13 (0.83) | MMP13 | |
| SCHEMBL7912740 | 0.80 | MMP13 (0.58) | MMP13 | |
| SCHEMBL1316531 | 0.80 | MMP13 (0.58) | MMP13 | |
| SCHEMBL1317251 | 0.80 | MMP13 (0.58) | MMP13 | |
| SCHEMBL1317323 | 0.77 | MMP13 (0.78) | MMP13 | |
| SCHEMBL1317320 | 0.77 | MMP13 (0.78) | MMP13 | |
| SCHEMBL7911602 | 0.74 | MMP13 (0.83) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056585-A2 | HETEROARYL DIAMIDE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-20 | — | — | WO | disclosed |