Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21339599 | 1.00 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL10306121 | 0.88 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL10306117 | 0.88 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL12647857 | 0.81 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL30184336 | 0.81 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL12367102 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL31463755 | 0.81 | CHRM2 (0.42) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL13497230 | 0.79 | CHRM2 (0.41) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL5157578 | 0.79 | CHRM2 (0.34) | CHRM2CHRM1CHRM4CHRM3KMT2A | |
| SCHEMBL20229519 | 0.79 | CHRM2 (0.34) | CHRM2CHRM1CHRM4CHRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211107-B1 | Process for expoxidizing prochiral olefins and a catalyst therefor and intermediates for making the catalyst | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-04-03 | — | — | US | disclosed |
| US-5616750-A | Compounds and process | SMITHKLINE BEECHAM PLC (GB) | 1997-04-01 | — | — | US | disclosed |