Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | PPARG | P37231 | 5/20 | 0.65 |
| ▸ | NCOA2 | Q15596 | 5/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.65 |
| ▸ | NCOA1 | Q15788 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | PRNP | P04156 | 1/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266309 | 0.84 | NOTUM (0.65) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL10440603 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7913006 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7902075 | 0.77 | CLCN2 (0.57) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7902562 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7902568 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL9551848 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7910151 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL7912983 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EPPARGNCOA2RXFP1 | |
| SCHEMBL9261365 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EPPARGNCOA2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211209-B1 | NONDEGRADING TISSUES, DRUGS, DIPHENYLAMINES | WARNER-LAMBERT COMPANY | 2001-04-03 | — | — | US | claimed |
| EP-0401857-A2 | Fenamate 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1990-12-12 | — | — | EP | claimed |
| US-6211209-B1 | NONDEGRADING TISSUES, DRUGS, DIPHENYLAMINES | WARNER-LAMBERT COMPANY | 2001-04-03 | — | — | US | disclosed |
| US-5462952-A | Have activity as inhibitors of 5-lipoxygenase and/or cyclooxygenase | WARNER-LAMBERT COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0401857-A2 | Fenamate 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1990-12-12 | — | — | EP | disclosed |