SCHEMBL7912958

SCHEMBL7912958

COCC1CCC(c2ccc(-c3ccc(C4CCC(CCCCCF)CC4)cc3F)cc2)CC1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.38
CYP2C9 P11712 3/20 0.38
APP P05067 2/20 0.36
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
ESR2 Q92731 2/20 0.33
FASN P49327 1/20 0.33
FFAR4 Q5NUL3 1/20 0.31
RORC P51449 1/20 0.31
DGAT1 O75907 1/20 0.30
SOAT1 P35610 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912954 1.00 CYP3A4 (0.38) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8218456 0.96 CYP3A4 (0.39) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8220318 0.90 CYP3A4 (0.39) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8216136 0.89 CYP2C9 (0.39) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL8214955 0.89 OPRL1 (0.33) CYP3A4CYP2C9ESR2OPRL1
SCHEMBL7910897 0.88 CYP2C9 (0.41) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL7912781 0.88 CYP3A4 (0.40) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL7910900 0.88 CYP2C9 (0.41) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL7912787 0.88 CYP3A4 (0.40) CYP3A4CYP2C9APPCYP2D6CYP2C19
SCHEMBL7910793 0.88 CYP3A4 (0.40) CYP3A4CYP2C9APPCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6174456-B1 STABILITY, LOW VISCOSITY AND HIGH TRANSITION TEMPERATURE OF THE ISOTROPIC PHASE CHISSO CORPORATION (JP) 2001-01-16 US disclosed
EP-0857708-A1 LIQUID CRYSTAL COMPOUNDS HAVING SUBSTITUTED ALKYL GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 1998-08-12 EP disclosed