Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218456 | 0.93 | CYP3A4 (0.39) | OPRL1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL8218522 | 0.89 | CYP2C9 (0.35) | OPRL1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7912958 | 0.89 | CYP3A4 (0.38) | OPRL1ESR2CYP2C9CYP3A4 | |
| SCHEMBL7912954 | 0.89 | CYP3A4 (0.38) | OPRL1ESR2CYP2C9CYP3A4 | |
| SCHEMBL8215975 | 0.88 | OPRL1 (0.38) | OPRL1CYP2C9CYP3A4 | |
| SCHEMBL8217737 | 0.87 | CYP2C9 (0.43) | OPRL1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7915918 | 0.86 | CYP2C9 (0.44) | OPRL1ESR2MEN1KMT2ACYP2C9 | |
| SCHEMBL7909664 | 0.86 | CYP2C9 (0.35) | OPRL1ESR2MEN1KMT2ACYP2C9 | |
| SCHEMBL7915916 | 0.86 | CYP2C9 (0.44) | OPRL1ESR2MEN1KMT2ACYP2C9 | |
| SCHEMBL7909669 | 0.86 | CYP2C9 (0.35) | OPRL1ESR2MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117361-A | FOUR RING COMPOUND HAVING AN ALKYL GROUP SUBSTITUTED WITH ONE OR MORE ETHERS, AND A HALOGEN ATOM SUBSTITUTED BENZENE RING; BROAD TEMPERATURE RANGE OF NEMATIC PHASE, HIGHER MISCIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS, AND CHEMICAL STABILITY | CHISSO CORP. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0891961-A1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED 1,4-PHENYLENE SKELETONS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-20 | — | — | EP | disclosed |