Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.63 |
| ▸ | MEN1 | O00255 | 9/20 | 0.63 |
| ▸ | HTT | P42858 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | DDX3X | O00571 | 2/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919379 | 0.86 | POLB (0.76) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL27406416 | 0.85 | MEN1 (0.67) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL30858683 | 0.85 | MEN1 (0.67) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL27941581 | 0.83 | SMN1; SMN2 (0.69) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL9170568 | 0.82 | EPHX1 (0.67) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL6297225 | 0.82 | MEN1 (0.70) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL3220438 | 0.81 | KMT2A (0.66) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL6297847 | 0.80 | KMT2A (0.67) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL5152659 | 0.80 | MEN1 (0.67) | KMT2AMEN1HTTMAPTPOLB | |
| SCHEMBL6152067 | 0.80 | CNR1 (0.52) | KMT2AMEN1HTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207809-B1 | CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND | CLARIANT GMBH (DE) | 2001-03-27 | — | — | US | disclosed |