Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565031 | 0.88 | CNR1 (0.55) | CNR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10781905 | 0.86 | MAPT (0.67) | CNR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10780462 | 0.84 | EPHX1 (0.61) | CNR1MAPTHTTALDH1A1EPHX1 | |
| SCHEMBL5561275 | 0.80 | CNR1 (0.53) | CNR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7913072 | 0.80 | KMT2A (0.63) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL16488794 | 0.75 | MAPT (0.56) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL7518954 | 0.75 | MAPT (0.67) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL10897950 | 0.74 | ALDH1A1 (0.65) | MAPTSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5565491 | 0.73 | MEN1 (0.46) | CNR1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13151453 | 0.73 | MEN1 (0.82) | CNR1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333792-A4 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P & G CLAIROL INC (US) | 2005-08-10 | — | — | EP | disclosed |
| US-6673966-B2 | FOR USE IN HAIR COLORING FORMULATIONS | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1333792-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P & G-Clairol, Inc. (US) | 2003-08-13 | — | — | EP | disclosed |
| US-20020100127-A1 | Novel coupler for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2002-08-01 | — | — | US | disclosed |
| WO-2002039967-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G - CLAIROL, INC. (US) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020100127-A1 | Novel coupler for use in oxidative hair dyeing | CBR1, CBR3, PYCR1 | CNR1 328/4885MAPT 4628/4885SMN1; SMN2 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.