Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578195 | 0.93 | CYP3A4 (0.43) | ADRA2ACYP3A4CYP1A2CYP2D6KCNH2 | |
| SCHEMBL3365274 | 0.91 | CHRM2 (0.53) | ADRA2ACYP3A4CYP1A2CYP2D6KCNH2 | |
| SCHEMBL7914136 | 0.86 | PTGDR2 (0.40) | ADRA2ACYP3A4CYP1A2CYP2D6KCNH2 | |
| SCHEMBL8524436 | 0.85 | CHRM2 (0.46) | ADRA2ACYP3A4CYP1A2CYP2D6KCNH2 | |
| SCHEMBL3364418 | 0.84 | PTGDR2 (0.38) | ADRA2ACYP3A4CYP1A2CYP2D6KCNH2 | |
| SCHEMBL8475476 | 0.83 | PTGDR2 (0.36) | ADRA2ACYP3A4CYP1A2CYP2D6KCNH2 | |
| SCHEMBL8473282 | 0.81 | PTGDR2 (0.35) | ADRA2ACYP3A4CYP1A2CYP2D6KCNH2 | |
| SCHEMBL290175 | 0.80 | TSHR (0.45) | ADRA2ACYP1A2CYP2D6KCNH2CHRM1 | |
| SCHEMBL25188997 | 0.78 | SLC6A2 (0.43) | ADRA2ACYP1A2CYP2D6KCNH2CHRM1 | |
| SCHEMBL11467456 | 0.77 | PTGDR2 (0.43) | SLC6A2SLC6A3MEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207852-B1 | THERAPY FOR INCONTINENCE; CROHN'S DISEASE; MUSCLE RELAXANTS | BRIDGE PHARMA, INC. | 2001-03-27 | — | — | US | disclosed |