Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239974 | 0.84 | TSHR (0.58) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL7237150 | 0.81 | TSHR (0.54) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL16579369 | 0.80 | TSHR (0.58) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL10907163 | 0.80 | TSHR (0.64) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL799844 | 0.79 | TSHR (0.62) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL17186797 | 0.78 | TSHR (0.50) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL3654239 | 0.77 | TSHR (0.60) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL18243045 | 0.77 | TSHR (0.60) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL29402968 | 0.77 | TSHR (1.00) | TSHRCYP3A4TDP1MAPK1CASR | |
| SCHEMBL1845000 | 0.77 | TSHR (1.00) | TSHRCYP3A4TDP1MAPK1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207695-B1 | INHIBITING GROWTH OF FUNGUS IN ASSOCIATION WITH A PLANT COMPRISING APPLYING TO THE LOCUS OF A PLANT A FUNGICIDALLY EFFECTIVE AMOUNT OF THE (S)-ENANTIOMER OF 1-(2-(2,4-DICHLOROPHENYL)-2-(2-PROPENYLOXY)ETHYL)-1H-IMIDAZOLE | CELGENE CORPORATION | 2001-03-27 | — | — | US | disclosed |