Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422598 | 1.00 | IDO1 (0.52) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2424845 | 0.82 | IDO1 (0.50) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15084293 | 0.82 | IDO1 (0.50) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10396656 | 0.82 | IDO1 (0.50) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL247092 | 0.80 | IDO1 (0.48) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL247767 | 0.80 | IDO1 (0.48) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10325517 | 0.80 | IDO1 (0.48) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10587518 | 0.79 | IDO1 (0.47) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8591917 | 0.79 | IDO1 (0.47) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3437067 | 0.79 | IDO1 (0.47) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207695-B1 | INHIBITING GROWTH OF FUNGUS IN ASSOCIATION WITH A PLANT COMPRISING APPLYING TO THE LOCUS OF A PLANT A FUNGICIDALLY EFFECTIVE AMOUNT OF THE (S)-ENANTIOMER OF 1-(2-(2,4-DICHLOROPHENYL)-2-(2-PROPENYLOXY)ETHYL)-1H-IMIDAZOLE | CELGENE CORPORATION | 2001-03-27 | — | — | US | disclosed |