Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915153 | 0.95 | MAPT (0.61) | MAPTENPP3CA2CA9TP53 | |
| SCHEMBL7918523 | 0.92 | MAPT (0.61) | MAPTENPP3CA2CA9TP53 | |
| SCHEMBL7915171 | 0.84 | NPSR1 (0.61) | MAPTENPP3CA2CA9GAA | |
| SCHEMBL7913343 | 0.83 | MAPT (0.67) | MAPTENPP3CA2CA9TP53 | |
| SCHEMBL3021512 | 0.83 | MAPT (0.81) | MAPTENPP3CA9TP53GAA | |
| SCHEMBL7918489 | 0.82 | MAPT (0.59) | MAPTENPP3CA2CA9TP53 | |
| SCHEMBL7918598 | 0.81 | EGFR (0.47) | MAPTENPP3CA2CA9TP53 | |
| SCHEMBL7905052 | 0.81 | MAPT (0.58) | MAPTENPP3CA2CA9TP53 | |
| SCHEMBL7915070 | 0.80 | NPSR1 (0.67) | MAPTENPP3CA2CA9GAA | |
| SCHEMBL3028283 | 0.80 | MAPT (0.67) | MAPTENPP3CA2CA9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |