Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912120 | 0.87 | MAPT (0.59) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL7913328 | 0.86 | KDR (0.69) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL7915153 | 0.85 | MAPT (0.61) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL7913343 | 0.85 | MAPT (0.67) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL7905464 | 0.83 | MAPT (0.63) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL8014060 | 0.83 | MAPT (0.66) | MAPTKDRCA9LMNAENPP3 | |
| SCHEMBL7913259 | 0.82 | CA9 (0.63) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL7914888 | 0.81 | MAPT (0.64) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL7913383 | 0.81 | MAPT (0.61) | MAPTTP53KDRCA9LMNA | |
| SCHEMBL7912189 | 0.80 | KDR (0.62) | MAPTTP53KDRCA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207666-B1 | TREATING PRECANCEROUS LESIONS BY ADMINISTERING 4-PHENYLPHTHALAZINE DERIVATIVE | CELL PATHWAYS, INC. | 2001-03-27 | — | — | US | disclosed |