Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28509572 | 0.98 | LTA4H (0.46) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Hydrochloric Acid SCHEMBL29054373 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Iodide SCHEMBL29054367 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Bromide SCHEMBL29054410 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Hydrochloric Acid SCHEMBL29054388 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Hydrochloric Acid SCHEMBL29054359 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Hydrochloric Acid SCHEMBL29054350 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Bromide SCHEMBL29054354 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Iodide SCHEMBL29054382 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A | |
| Hydrochloric Acid SCHEMBL29054395 | 0.97 | LTA4H (0.45) | LTA4HHTR1ASLC6A3CYP2D6SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215001-B1 | ANTIINFLAMMATORY AGENTS, ANTIASTHMATICS, AND ANTIALLERGENS; SIDE EFFECT REDUCTION | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-04-10 | — | — | US | disclosed |