Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784527 | 0.92 | TRPV1 (0.49) | MALT1TRPV1ALDH1A1HTR1FHTR1A | |
| SCHEMBL1781523 | 0.87 | TRPV1 (0.49) | MALT1TRPV1ALDH1A1 | |
| SCHEMBL615159 | 0.83 | JAK2 (0.41) | TRPV1 | |
| SCHEMBL1783734 | 0.81 | TRPV1 (0.44) | TRPV1ALDH1A1HTR1FHTR1AHTR1B | |
| SCHEMBL616240 | 0.81 | JAK2 (0.43) | TRPV1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1781429 | 0.80 | TRPV1 (0.44) | TRPV1ALDH1A1HTR1FHTR1AHTR1B | |
| SCHEMBL1782304 | 0.80 | TRPV1 (0.47) | MALT1TRPV1ALDH1A1 | |
| SCHEMBL614007 | 0.80 | JAK2 (0.45) | TRPV1ALDH1A1 | |
| SCHEMBL615155 | 0.79 | MALT1 (0.43) | MALT1TRPV1 | |
| Hydrochloric Acid SCHEMBL2364885 | 0.78 | TRPV1 (0.37) | TRPV1ALDH1A1HTR1FHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120183579-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2012-07-19 | — | — | US | disclosed |
| WO-2010039236-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183579-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | CXCL8, CCR1, CCR8 | MALT1 138/4885TRPV1 92/4885ALDH1A1 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.