Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815869 | 0.86 | TRPV1 (0.41) | TRPV1ALDH1A1NTRK1LMNAGAA | |
| SCHEMBL20480671 | 0.80 | CYP3A4 (0.37) | TRPV1CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL7909655 | 0.80 | CNR1 (0.40) | TRPV1CNR1CNR2ALDH1A1LMNA | |
| SCHEMBL29736130 | 0.77 | TRPV1 (0.38) | ATMTRPV1ALDH1A1LMNAGAA | |
| SCHEMBL22997112 | 0.75 | TRPV1 (0.37) | TRPV1CNR1CNR2LMNA | |
| SCHEMBL3580439 | 0.75 | MEN1 (0.43) | TRPV1CNR1CNR2LMNA | |
| SCHEMBL31253977 | 0.75 | MEN1 (0.43) | TRPV1CNR1CNR2LMNA | |
| SCHEMBL15021653 | 0.75 | MEN1 (0.43) | TRPV1CNR1CNR2LMNA | |
| SCHEMBL29654106 | 0.75 | TRPV1 (0.37) | TRPV1CNR1CNR2LMNA | |
| SCHEMBL1237664 | 0.75 | TRPV1 (0.37) | TRPV1CNR1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |