Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913670 | 0.80 | ATM (0.44) | CNR1CNR2TRPV1ALDH1A1LMNA | |
| SCHEMBL7900351 | 0.76 | KCNE1 (0.41) | CNR1CNR2MEN1KMT2AMAPT | |
| SCHEMBL7909723 | 0.75 | HDAC1 (0.41) | CNR1CNR2 | |
| SCHEMBL7909660 | 0.74 | TRPV1 (0.30) | TRPV1 | |
| SCHEMBL7910189 | 0.74 | KCNE1 (0.41) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2184227 | 0.70 | AKR1B1 (0.40) | FPR2MEN1KMT2ATRPV1MAPT | |
| SCHEMBL20480671 | 0.70 | CYP3A4 (0.37) | CNR1CNR2MEN1KMT2ATRPV1 | |
| SCHEMBL10382338 | 0.69 | PTGDR2 (0.41) | MEN1KMT2ATRPV1MAPTALDH1A1 | |
| SCHEMBL10382710 | 0.66 | CTSD (0.39) | TRPV1MAPTALDH1A1HTTTAAR1 | |
| SCHEMBL8946767 | 0.66 | KCNE1 (0.37) | MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177449-B1 | CARDIOVASCULAR DISORDERS; ANTIULCER AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-01-23 | — | — | US | disclosed |