Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | FASN | P49327 | 1/20 | 1.00 |
| ▸ | KAT2A | Q92830 | 3/20 | 0.77 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913812 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| (+/-)-Protolichesterinic Acid SCHEMBL7913885 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL2993206 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL6428925 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL360509 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL7920753 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL7920321 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| SCHEMBL3007085 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| Protolichesterinic Acid SCHEMBL7913878 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA | |
| Protolichesterinic Acid SCHEMBL7913888 | 1.00 | POLB (1.00) | POLBFASNKAT2ADAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869784-A4 | INHIBITION OF FATTY ACID SYNTHASE AS A MEANS TO REDUCE ADIPOCYTE MASS | UNIV JOHNS HOPKINS (US) | 2001-02-07 | — | — | EP | disclosed |
| US-5981575-A | INDUCING WEIGHT LOSS IN AN ANIMAL BY ADMINISTERING TO THE ANIMAL A COMPOUND WHICH REDUCES FATTY ACID SYNTHASE (FAS) ACTIVITY IN ADIPOCYTES OR LIVER CELLS; 5-SUBSTITUTED 2-OXO-3-METHYLENE-4-FURANCARBOXYLIC ACID | JOHNS HOPKINS UNIVERSITY, THE (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0869784-A1 | INHIBITION OF FATTY ACID SYNTHASE AS A MEANS TO REDUCE ADIPOCYTE MASS | THE JOHNS HOPKINS UNIVERSITY (US) | 1998-10-14 | — | — | EP | disclosed |