SCHEMBL7913848

SCHEMBL7913848

CCCc1ccc(-c2ccc(-c3ccc(C#N)cc3)cc2F)cc1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
HSD17B10 Q99714 1/20 0.54
KIF11 P52732 1/20 0.47
HRH3 Q9Y5N1 7/20 0.46
KDM1A O60341 2/20 0.44
RARB P10826 3/20 0.43
NSD2 O96028 1/20 0.43
PDE3B Q13370 1/20 0.43
PDE3A Q14432 1/20 0.43
CYP2A6 P11509 1/20 0.42
RORC P51449 1/20 0.42
RARA P10276 1/20 0.40
RARG P13631 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637013 1.00 TSHR (0.54) TSHRHSD17B10KIF11HRH3KDM1A
SCHEMBL9406878 1.00 TSHR (0.54) TSHRHSD17B10KIF11HRH3KDM1A
SCHEMBL17108410 0.93 TSHR (0.51) TSHRHSD17B10KIF11HRH3KDM1A
SCHEMBL20152480 0.92 TSHR (0.62) TSHRHSD17B10KIF11HRH3KDM1A
SCHEMBL8376669 0.91 TSHR (0.49) TSHRHSD17B10HRH3KDM1ARARB
SCHEMBL17225165 0.91 TSHR (0.69) TSHRHSD17B10KIF11HRH3RARB
SCHEMBL8466430 0.89 TSHR (0.48) TSHRHSD17B10HRH3KDM1ARARB
SCHEMBL17946137 0.88 CYP2A6 (0.58) TSHRHSD17B10KIF11HRH3KDM1A
SCHEMBL10603849 0.88 RARB (0.51) HSD17B10KIF11RARBRARARARG
SCHEMBL9512294 0.88 RARB (0.51) HSD17B10KIF11RARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573599-A Photoisomerizable chiral molecules and application thereof in realizing color liquid crystal film patterning 苏州大学 2022-06-03 CN disclosed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-5958290-A ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-09-28 US disclosed
EP-0394417-B2 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-08-04 EP disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
US-5476611-A Polymer dispersed liquid crystal MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-12-19 US disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
EP-0452460-B1 ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM MERCK PATENT GMBH (DE) 1995-01-18 EP disclosed
US-5344587-A Nitriles MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-09-06 US disclosed
EP-0366985-B1 Super twist liquid crystal display MERCK PATENT GMBH (DE) 1994-04-06 EP disclosed
EP-0564869-A1 Electrooptical liquid crystal systems MERCK PATENT GmbH (DE) 1993-10-13 EP disclosed
EP-0452460-A1 ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM. MERCK PATENT GMBH (DE) 1991-10-23 EP disclosed
WO-1991005029-A1 ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-04-18 WO disclosed
EP-0366985-A1 Super twist liquid crystal display MERCK PATENT GmbH (DE) 1990-05-09 EP disclosed
WO-1990004622-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed