Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 11/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903639 | 0.99 | MAPT (0.40) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7911206 | 0.99 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7914043 | 0.96 | MAPT (0.39) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7914131 | 0.91 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7917585 | 0.89 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7917467 | 0.86 | CYP3A4 (0.39) | ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL9074860 | 0.86 | MAPT (0.40) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL9074854 | 0.86 | MAPT (0.40) | ALDH1A1LMNAMAPTCYP2C9MEN1 | |
| SCHEMBL7911910 | 0.85 | MAPT (0.33) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9717221 | 0.85 | MAPT (0.40) | ALDH1A1LMNAMAPTCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640578-B2 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0640578-B1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | CHISSO CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0640578-A1 | Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition | Chisso Corporation (JP) | 1995-03-01 | — | — | EP | disclosed |