SCHEMBL7914054

SCHEMBL7914054

O=C=Nc1ccc(Cc2ccc(NC(=O)OCCOC(=O)Nc3ccc(Cc4ccc(N=C=O)cc4)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
CYP3A4 P08684 1/20 0.57
SMN1; SMN2 Q16637 6/20 0.44
NPC1 O15118 6/20 0.44
RAB9A P51151 6/20 0.44
CYP1A2 P05177 1/20 0.44
RECQL P46063 1/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 2/20 0.40
SAE1 Q9UBE0 2/20 0.40
UBA2 Q9UBT2 2/20 0.40
HPGD P15428 2/20 0.39
CASP1 P29466 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
MCL1 Q07820 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13411438 0.94 TSHR (0.54) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL12948610 0.94 CYP3A4 (0.54) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL17547464 0.94 TSHR (0.50) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL12013953 0.93 TSHR (0.53) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL12972370 0.92 SMN1; SMN2 (0.52) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL25669688 0.91 CYP3A4 (0.48) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL13170271 0.90 TSHR (0.49) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL17281037 0.90 TSHR (0.49) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL17232006 0.89 TSHR (0.46) TSHRCYP3A4SMN1; SMN2NPC1RAB9A
SCHEMBL873550 0.89 TSHR (0.54) TSHRCYP3A4SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124683-B2 Reactive hot melt adhesive composition H.B. FULLER COMPANY (US) 2021-09-21 US disclosed
EP-3433296-B1 REACTIVE HOT MELT ADHESIVE COMPOSITION FULLER H B CO (US) 2020-11-25 EP disclosed
US-20190264079-A1 REACTIVE HOT MELT ADHESIVE COMPOSITION JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2019-08-29 US disclosed
US-10316227-B2 Reactive hot melt adhesive composition H.B. FULLER COMPANY 2019-06-11 US disclosed
US-20170275512-A1 REACTIVE HOT MELT ADHESIVE COMPOSITION JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2017-09-28 US disclosed
WO-2017165652-A1 REACTIVE HOT MELT ADHESIVE COMPOSITION H.B. FULLER COMPANY (US) 2017-09-28 WO disclosed
US-7811342-B1 Coated abrasive tools from non-blocked urethane prepolymer SAINT-GOBAIN ABRASIVES, INC. (US) 2010-10-12 US disclosed
US-20070262031-A1 Industrial Process for Recycling Waste Its Applications and Products Obtained GIOVANNI MAURIZIO D 2007-11-15 US disclosed
US-20070262031-A1 Industrial Process for Recycling Waste Its Applications and Products Obtained GIOVANNI MAURIZIO D 2007-11-15 US disclosed
US-6232266-B1 COMPRISES TWO OR MORE KINDS OF COMPOUNDS, AND AT LEAST ONE OF WHICH IS FORMED A COLOR-FORMATION CONTROLLING LAYER OBTAINED BY POLYMERIZING A COMPOUND HAVING AN UNSATURATED CARBON BOND. MITSUBISHI PAPER MILLS LIMITED (JP) 2001-05-15 US disclosed