SCHEMBL873550

SCHEMBL873550

CCOC(=O)Nc1ccc(Cc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
CYP3A4 P08684 2/20 0.54
RAB9A P51151 5/20 0.48
NPC1 O15118 4/20 0.48
HPGD P15428 3/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
SMN1; SMN2 Q16637 4/20 0.45
ALDH1A1 P00352 3/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 1/20 0.44
RECQL P46063 1/20 0.44
CYP2C9 P11712 3/20 0.43
CYP2C19 P33261 3/20 0.43
CYP2D6 P10635 2/20 0.43
CYP1A2 P05177 3/20 0.43
MTNR1B P49286 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10712510 0.93 RAB9A (0.54) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL12972370 0.90 SMN1; SMN2 (0.52) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL10444774 0.89 RAB9A (0.50) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL7914054 0.89 TSHR (0.57) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL25669688 0.89 CYP3A4 (0.48) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL13008184 0.87 TSHR (0.59) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL13411438 0.86 TSHR (0.54) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL12948610 0.86 CYP3A4 (0.54) TSHRCYP3A4RAB9ANPC1HPGD
SCHEMBL14453248 0.86 TSHR (0.57) TSHRCYP3A4LMNACYP1A2MAPT
SCHEMBL17547464 0.86 TSHR (0.50) TSHRCYP3A4RAB9ANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2619273-B1 COATING COMPOSITION FOR METAL CONDUCTORS COATINGS FOREIGN IP CO LLC (US) 2015-07-01 EP claimed
EP-2619273-A2 COATING COMPOSITION FOR METAL CONDUCTORS Coatings Foreign IP Co. LLC (US) 2013-07-31 EP claimed
US-20130133920-A1 COATING COMPOSITION FOR METAL CONDUCTORS EI DU PONT DE NEMOURS AND COMPANY (US) 2013-05-30 US claimed
WO-2012040180-A2 COATING COMPOSITION FOR METAL CONDUCTORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-29 WO claimed
EP-2619273-B1 COATING COMPOSITION FOR METAL CONDUCTORS COATINGS FOREIGN IP CO LLC (US) 2015-07-01 EP disclosed
EP-2619273-A2 COATING COMPOSITION FOR METAL CONDUCTORS Coatings Foreign IP Co. LLC (US) 2013-07-31 EP disclosed
US-20130133920-A1 COATING COMPOSITION FOR METAL CONDUCTORS EI DU PONT DE NEMOURS AND COMPANY (US) 2013-05-30 US disclosed
WO-2012040180-A2 COATING COMPOSITION FOR METAL CONDUCTORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-29 WO disclosed
US-5043471-A Process for the preparation of polyisocyanates BAYER AKTIENGESELLSCHAFT (DE) 1991-08-27 US disclosed