SCHEMBL7914155

SCHEMBL7914155

CCC1CCC(c2ccc(C#Cc3ccc(OC(F)(F)C(F)C(F)(F)F)c(F)c3)cc2)CC1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.32
PDE2A O00408 1/20 0.30
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7917449 0.93 CYP2C9 (0.37) RECQL
SCHEMBL7913523 0.90 CYP2C9 (0.31) RECQL
SCHEMBL8834377 0.89 ACACB (0.32) ACACB
SCHEMBL7914081 0.85 ALDH1A1 (0.39) ACACB
SCHEMBL8834050 0.82 RECQL (0.30) RECQL
SCHEMBL7911260 0.82 CYP2C9 (0.37) ACACB
SCHEMBL7914009 0.81 ACACB (0.34) ACACB
SCHEMBL7911864 0.81 CYP2C9 (0.39) RECQLPDE2A
SCHEMBL8834299 0.79 CYP2C9 (0.31) ACACB
SCHEMBL7914144 0.79 CYP2C9 (0.39) RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B2 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 2001-06-27 EP disclosed
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed