Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.52 |
| ▸ | CA1 | P00915 | 10/20 | 0.52 |
| ▸ | CA9 | Q16790 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144234 | 0.85 | CA2 (0.53) | CA2CA1CA9CA12CA14 | |
| SCHEMBL11481986 | 0.85 | CA2 (0.53) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7146350 | 0.83 | CA2 (0.52) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7137651 | 0.80 | CA2 (0.47) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7137010 | 0.77 | CA2 (0.57) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7141530 | 0.76 | CA2 (0.55) | CA2CA1CA9CA12CA14 | |
| SCHEMBL14530792 | 0.74 | CPN1 (0.47) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7913948 | 0.73 | CA2 (0.47) | CA2CA1CA9CA12CA14 | |
| SCHEMBL7145706 | 0.73 | CA2 (0.52) | CA2CA1CA9CA12CA14 | |
| SCHEMBL23364593 | 0.73 | CA2 (0.61) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |