SCHEMBL7914478

SCHEMBL7914478

COC(C)O[Si](OC(C)OC)(OC(C)OC)C(C)C#N

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379030 0.74 TSHR (0.37) TSHR
SCHEMBL28960973 0.67 TSHR (0.35) TSHR
SCHEMBL49922 0.64
Acetonitrile SCHEMBL6245822 0.64
SCHEMBL6796444 0.64
SCHEMBL10877518 0.63 TSHR (0.32) TSHR
Water SCHEMBL5322619 0.62
Water SCHEMBL1269330 0.62
SCHEMBL2198737 0.62
Thiocyanic Acid SCHEMBL7093925 0.62 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5420196-A Polyacrylate adhesion GENERAL ELECTRIC COMPANY (US) 1995-05-30 US claimed
US-5232982-A Having fillers, plasticizers, cyano-silane promoters, disilazane stabilizers, tin diketonate complex curing agents; stable, fast cure GENERAL ELECTRIC COMPANY (US) 1993-08-03 US claimed
US-5213899-A ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1993-05-25 US claimed
EP-0735086-B1 1-Component alkoxy curing RTV silicone sealant compositions GEN ELECTRIC (US) 2001-10-10 EP disclosed
US-5962559-A CONTAINING 1-SILA-AZACYCLOPENTANE COMPOUNDS AS ALCOHOL SCAVENGERS GENERAL ELECTRIC COMPANY (US) 1999-10-05 US disclosed
EP-0905195-A1 Neutral cure one component room temperature vulcanizable silicone compositions GENERAL ELECTRIC COMPANY (US) 1999-03-31 EP disclosed
EP-0735086-A2 1-Component alkoxy curing RTV silicone sealant compositions GENERAL ELECTRIC COMPANY (US) 1996-10-02 EP disclosed
US-5519104-A DIALKYLTIN DIALKANOATE CURING CATALYST GENERAL ELECTRIC COMPANY (US) 1996-05-21 US disclosed
EP-0495298-B1 Improved room-temperature vulcanizable silicone compositions and process for their preparation GEN ELECTRIC (US) 1996-02-07 EP disclosed
EP-0493887-B1 Improved room temperature vulcanizable silicone compositions GEN ELECTRIC (US) 1996-02-07 EP disclosed
US-5489479-A POLYDIORGANOSILOXANE, DIORGANOTIN BIS BETA-DIKETONATE CONDENSATION CATALYST, SCAVENGER FOR HYDROXY FUNCTIONAL GROUPS, AND ADHESION PROMOTING POLYALKOXYSILANE GENERAL ELECTRIC COMPANY (US) 1996-02-06 US disclosed
EP-0565309-A1 Silicone compositions GENERAL ELECTRIC COMPANY (US) 1993-10-13 EP disclosed
US-5232982-A Having fillers, plasticizers, cyano-silane promoters, disilazane stabilizers, tin diketonate complex curing agents; stable, fast cure GENERAL ELECTRIC COMPANY (US) 1993-08-03 US disclosed
US-5213899-A ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1993-05-25 US disclosed
EP-0495298-A1 Improved room-temperature vulcanizable silicone compositions and process for their preparation GENERAL ELECTRIC COMPANY (US) 1992-07-22 EP disclosed
EP-0493887-A1 Improved room temperature vulcanizable silicone compositions GENERAL ELECTRIC COMPANY (US) 1992-07-08 EP disclosed
EP-0491482-A1 Room temperature vulcanizable silicone compositions having improved low modulus GENERAL ELECTRIC COMPANY (US) 1992-06-24 EP disclosed
EP-0491483-A1 Adhesion promoter system for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1992-06-24 EP disclosed
US-4528353-A Adhesion promoters for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1985-07-09 US disclosed
US-4483973-A Adhesion promoters for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1984-11-20 US disclosed