⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367715 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL10877518 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL19356743 | 0.74 | PIK3CD (0.36) | — | |
| SCHEMBL379030 | 0.71 | TSHR (0.37) | — | |
| SCHEMBL19356674 | 0.68 | — | — | |
| SCHEMBL27705593 | 0.65 | — | — | |
| SCHEMBL19356731 | 0.64 | PIK3CD (0.31) | — | |
| SCHEMBL16329828 | 0.64 | PIK3CD (0.31) | — | |
| SCHEMBL7914478 | 0.64 | TSHR (0.30) | — | |
| Acetonitrile SCHEMBL4300315 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420196-A | Polyacrylate adhesion | GENERAL ELECTRIC COMPANY (US) | 1995-05-30 | — | — | US | claimed |
| US-5232982-A | Having fillers, plasticizers, cyano-silane promoters, disilazane stabilizers, tin diketonate complex curing agents; stable, fast cure | GENERAL ELECTRIC COMPANY (US) | 1993-08-03 | — | — | US | claimed |
| US-5213899-A | ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1993-05-25 | — | — | US | claimed |
| EP-0735086-B1 | 1-Component alkoxy curing RTV silicone sealant compositions | GEN ELECTRIC (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5962559-A | CONTAINING 1-SILA-AZACYCLOPENTANE COMPOUNDS AS ALCOHOL SCAVENGERS | GENERAL ELECTRIC COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0735086-A2 | 1-Component alkoxy curing RTV silicone sealant compositions | GENERAL ELECTRIC COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5519104-A | DIALKYLTIN DIALKANOATE CURING CATALYST | GENERAL ELECTRIC COMPANY (US) | 1996-05-21 | — | — | US | disclosed |
| EP-0495298-B1 | Improved room-temperature vulcanizable silicone compositions and process for their preparation | GEN ELECTRIC (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0493887-B1 | Improved room temperature vulcanizable silicone compositions | GEN ELECTRIC (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5489479-A | POLYDIORGANOSILOXANE, DIORGANOTIN BIS BETA-DIKETONATE CONDENSATION CATALYST, SCAVENGER FOR HYDROXY FUNCTIONAL GROUPS, AND ADHESION PROMOTING POLYALKOXYSILANE | GENERAL ELECTRIC COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-5420196-A | Polyacrylate adhesion | GENERAL ELECTRIC COMPANY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5232982-A | Having fillers, plasticizers, cyano-silane promoters, disilazane stabilizers, tin diketonate complex curing agents; stable, fast cure | GENERAL ELECTRIC COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5213899-A | ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| EP-0495298-A1 | Improved room-temperature vulcanizable silicone compositions and process for their preparation | GENERAL ELECTRIC COMPANY (US) | 1992-07-22 | — | — | EP | disclosed |
| EP-0493887-A1 | Improved room temperature vulcanizable silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1992-07-08 | — | — | EP | disclosed |
| EP-0491482-A1 | Room temperature vulcanizable silicone compositions having improved low modulus | GENERAL ELECTRIC COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0491483-A1 | Adhesion promoter system for one-component RTV silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| US-4528353-A | Adhesion promoters for one-component RTV silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1985-07-09 | — | — | US | disclosed |
| US-4483973-A | Adhesion promoters for one-component RTV silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1984-11-20 | — | — | US | disclosed |