Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.56 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29609270 | 1.00 | HSD17B10 (0.58) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL29371193 | 0.86 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL30641561 | 0.86 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL23610907 | 0.86 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL15412933 | 0.84 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL29608904 | 0.84 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL647719 | 0.83 | HSD17B10 (0.58) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL30032675 | 0.79 | HSD17B10 (0.56) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL15800694 | 0.79 | PLD1 (0.73) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL21353591 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221810-B1 | 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2001-04-24 | — | — | US | disclosed |
| US-5780394-A | EFFECTIVE AGAINST CHEMICAL RESISTANT PESTS; PESTICIDES, HERBIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| US-5739389-A | INSECTICIDE; HERBICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-04-14 | — | — | US | disclosed |
| US-5661110-A | PESTICIDES; INSECTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-26 | — | — | US | disclosed |
| EP-0508126-B1 | 3-Hydroxy-4-aryl-5-oxo-pyrazolin derivatives | BAYER AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| US-5474974-A | Insecticide, pesticide, nematocide, miticide and herbicide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5358924-A | Pesticides, miticides, insecticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-25 | — | — | US | disclosed |
| US-5332720-A | 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-26 | — | — | US | disclosed |
| EP-0508126-A1 | 3-Hydroxy-4-aryl-5-oxo-pyrazolin derivatives | BAYER AG (DE) | 1992-10-14 | — | — | EP | disclosed |