Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | TSHR | P16473 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29608904 | 1.00 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL29608764 | 0.90 | HSD17B10 (0.55) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL30641561 | 0.87 | HSD17B10 (0.61) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL647719 | 0.84 | HSD17B10 (0.58) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL29609270 | 0.84 | HSD17B10 (0.58) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL7914550 | 0.84 | HSD17B10 (0.58) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL29972830 | 0.84 | ALDH1A1 (0.54) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL12194223 | 0.83 | HSD17B10 (0.56) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL22532812 | 0.82 | ALDH1A1 (0.62) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL30032675 | 0.81 | HSD17B10 (0.56) | HSD17B10ALDH1A1HPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200207720-A1 | BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
| EP-2872507-A1 | AZAINDOLE DERIVATIVES WHICH ACT AS PI3K INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014011568-A1 | AZAINDOLE DERIVATIVES WHICH ACT AS PI3K INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207720-A1 | BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | ADORA1, ADORA2A, ADORA3 | HSD17B10 4092/4885ALDH1A1 1065/4885HPGD 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.