Biphenyl

Biphenyl

SCHEMBL7914650

COc1ccc(OC)c(CO)c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.57
IDO1 P14902 2/20 0.51
ADRA1A P35348 1/20 0.51
TAAR1 Q96RJ0 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HIF1A Q16665 1/20 0.49
HTR2A P28223 1/20 0.49
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TAS1R3 Q7RTX0 2/20 0.47
TAS1R1 Q7RTX1 2/20 0.47
AOC3 Q16853 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487944 0.89 HSD17B10 (0.62) HSD17B10IDO1ADRA1ATAAR1HTR2A
SCHEMBL27965221 0.86 KDM4E (0.55) HSD17B10KMT2AKDM4EALDH1A1
SCHEMBL27821291 0.83 BAZ2B (0.53) HSD17B10MEN1KMT2AKDM4EALDH1A1
SCHEMBL28008454 0.80 PDCD1 (0.55) HSD17B10MEN1KMT2AKDM4EALDH1A1
SCHEMBL25591930 0.80 MTNR1A (0.60)
SCHEMBL7273091 0.80 MAOB (0.55) HIF1AALDH1A1
SCHEMBL30211932 0.80 MTNR1A (0.60)
Biphenyl SCHEMBL15563275 0.78 POLB (0.51) MEN1KMT2AKDM4EALDH1A1
SCHEMBL1638961 0.78 HSD17B10 (0.46) HSD17B10IDO1ADRA1ATAAR1HTR2A
SCHEMBL5569940 0.78 HSD17B10 (0.51) HSD17B10MEN1KMT2AHIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124671-A1 BIO-OIL PRESERVATIVES Ensyn Technologies Inc. (CA) 2001-08-22 EP claimed
WO-2000025996-A1 BIO-OIL PRESERVATIVES ENSYN TECHNOLOGIES INC. (CA) 2000-05-11 WO claimed