SCHEMBL7914686

SCHEMBL7914686

CCCCCCCCCCCCCCCCCCCCCC(=O)NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
ASAH1 Q13510 1/20 0.51
MAPK1 P28482 1/20 0.46
HSP90AA1 P07900 1/20 0.46
DNM1 Q05193 2/20 0.45
NAAA Q02083 1/20 0.45
DEGS1 O15121 1/20 0.45
CASP2 P42575 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788541 1.00 FAAH (0.53) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL28417284 1.00 FAAH (0.53) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL22575879 1.00 FAAH (0.53) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL31472777 1.00 FAAH (0.53) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL12359197 1.00 FAAH (0.53) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL31472778 1.00 FAAH (0.53) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL18992757 0.98 FAAH (0.50) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL28446577 0.98 FAAH (0.50) FAAHMEN1KMT2AASAH1MAPK1
SCHEMBL22467337 0.93 KDM4E (0.46) FAAHMEN1KMT2AASAH1NAAA
SCHEMBL15057658 0.93 KDM4E (0.46) FAAHMEN1KMT2AASAH1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210691-B1 LIPOPHILIC DERIVATIVES OF AMINO DEOXYALDITOLS, SHAMPOOS AND HAIR CONDITIONERS L'OREAL (FR) 2001-04-03 US disclosed
US-6001376-A COSMETIC COMPOSITIONS FOR THE TREATMENT OF KERATINOUS SUBSTANCES AND FOR BUCCODENTAL HYGIENE L'OREAL (FR) 1999-12-14 US disclosed
EP-0648204-B1 AMINO DEOXYALDITOL LIPOPHILIC DERIVATIVES FOR USE IN COSMETICS, COSMETIC COMPOSITIONS CONTAINING SAME AND NOVEL ALKYL CARBAMATES OREAL (FR) 1998-11-18 EP disclosed
US-5616746-A SKIN AND HAIR TREATMENT L'OREAL 1997-04-01 US disclosed