Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 20/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 13/20 | 0.49 |
| ▸ | PDE6D | O43924 | 3/20 | 0.42 |
| ▸ | PDE6A | P16499 | 3/20 | 0.42 |
| ▸ | PDE6G | P18545 | 3/20 | 0.42 |
| ▸ | PDE6B | P35913 | 3/20 | 0.42 |
| ▸ | PDE6C | P51160 | 3/20 | 0.42 |
| ▸ | PDE6H | Q13956 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323718 | 0.84 | PDE2A (0.51) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL3323059 | 0.78 | PDE2A (0.62) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL3326026 | 0.74 | PDE2A (0.75) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL3325917 | 0.73 | PDE2A (0.42) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL2791202 | 0.69 | PDE2A (0.60) | PDE2APDE10A | |
| SCHEMBL3327358 | 0.69 | PDE2A (0.74) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL3324738 | 0.69 | PDE2A (0.67) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL12502455 | 0.68 | PDE2A (1.00) | PDE2APDE10A | |
| SCHEMBL3326270 | 0.67 | PDE2A (0.64) | PDE2APDE10APDE6DPDE6APDE6G | |
| SCHEMBL12502195 | 0.66 | PDE2A (1.00) | PDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054260-A1 | IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES | BIOTIE THERAPIES GMBH (DE) | 2010-05-14 | — | — | WO | disclosed |