Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL28069683 | 0.80 | SLC13A5 (0.43) | ALDH1A1 | |
| SCHEMBL203784 | 0.78 | F7 (0.48) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29618028 | 0.76 | F7 (0.47) | ALDH1A1 | |
| SCHEMBL29127794 | 0.76 | F7 (0.47) | ALDH1A1 | |
| SCHEMBL1150908 | 0.76 | F7 (0.47) | ALDH1A1 | |
| SCHEMBL27708731 | 0.76 | DYRK1A (0.47) | ALDH1A1 | |
| Phosphoric Acid SCHEMBL3485885 | 0.75 | F7 (0.40) | ALDH1A1 | |
| Benzotriazole SCHEMBL9790704 | 0.70 | F7 (0.41) | ALDH1A1 | |
| Citric Acid SCHEMBL27575034 | 0.67 | ALDH1A1 (0.79) | ACLYALDH1A1 | |
| Citric Acid SCHEMBL31129161 | 0.67 | CYP3A4 (0.56) | ACLYALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101380793-B | Solution casting method and apparatus | FUJI PHOTO FILM CO LTD | 2013-09-11 | — | — | CN | disclosed |
| CN-101380793-A | Solution casting method and apparatus | FUJIFILM CORP (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-101139447-A | Method and system for producing cellulose acylate film | FUJIFILM CORP (JP) | 2008-03-12 | — | — | CN | disclosed |
| US-6180323-B1 | PREPARING PHOTOPOLYMERIZABLE ELEMENT COMPRISING SUPPORT AND PHOTOPOLYMERIZABLE FORMULATION; APPLYING TO COPPER CLAD SUBSTRATE; IMAGEWISE EXPOSING TO ACTINIC RADIATION; DEVELOPING TO FORM RESIST IMAGE ON COPPER CLAD SUBSTRATE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-01-30 | — | — | US | disclosed |
| US-5962190-A | BINDER OF C4-10 ALKYL METHACRYLATE, C4-10 ALKYL ACRYLATE, METHYL METHACRYLATE OR ETHYL METHACRYLATE, METHACRYLIC ACID OR ACRYLIC ACID, AND STYRENE; UNSATURATED CROSSLINKING AGENT; PHOTOINITIATOR; RELIEF IMAGES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0909990-A2 | Photopolymerizable compositions having improved sidewall geometry and development latitude | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-04-21 | — | — | EP | disclosed |