Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7927257 | 1.00 | GRM2 (0.32) | GRM2KDM4ERAD52MAPTALDH1A1 | |
| SCHEMBL7926084 | 0.84 | KDM4E (0.38) | GRM2KDM4ERAD52MAPTALDH1A1 | |
| SCHEMBL7922728 | 0.84 | GRM2 (0.36) | GRM2KDM4ERAD52MAPTALDH1A1 | |
| SCHEMBL7928160 | 0.84 | GRM2 (0.48) | GRM2KDM4ERAD52 | |
| SCHEMBL7924595 | 0.84 | GRM2 (0.48) | GRM2KDM4ERAD52 | |
| SCHEMBL2220917 | 0.84 | GRM2 (0.35) | GRM2KDM4EALDH1A1 | |
| SCHEMBL12441129 | 0.84 | GRM2 (0.35) | GRM2KDM4EALDH1A1 | |
| SCHEMBL2220997 | 0.84 | KDM4E (0.35) | KDM4EMAPTALDH1A1HSD17B10TLR8 | |
| SCHEMBL2220435 | 0.84 | KDM4E (0.35) | KDM4EMAPTALDH1A1HSD17B10TLR8 | |
| SCHEMBL7918388 | 0.81 | PTAFR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036544-A1 | OXAZOLOBENZIMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-04-01 | — | — | WO | disclosed |