Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 19/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924595 | 1.00 | GRM2 (0.48) | GRM2KDM4ERAD52 | |
| SCHEMBL7926084 | 0.88 | KDM4E (0.38) | GRM2KDM4ERAD52 | |
| SCHEMBL7922728 | 0.88 | GRM2 (0.36) | GRM2KDM4ERAD52 | |
| SCHEMBL7915024 | 0.84 | GRM2 (0.32) | GRM2KDM4ERAD52 | |
| SCHEMBL7927257 | 0.84 | GRM2 (0.32) | GRM2KDM4ERAD52 | |
| SCHEMBL12441128 | 0.83 | GRM2 (0.50) | GRM2KDM4E | |
| SCHEMBL12441180 | 0.83 | GRM2 (0.50) | GRM2KDM4E | |
| SCHEMBL7923909 | 0.83 | GRM2 (0.47) | GRM2 | |
| SCHEMBL2219269 | 0.83 | GRM2 (0.47) | GRM2 | |
| SCHEMBL7922412 | 0.83 | GRM2 (0.47) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036544-A1 | OXAZOLOBENZIMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2010-04-01 | — | — | WO | disclosed |