Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463940 | 1.00 | TSHR (0.42) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL27692867 | 1.00 | TSHR (0.42) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL27972170 | 1.00 | TSHR (0.42) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL20076569 | 1.00 | TSHR (0.42) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL27744129 | 1.00 | TSHR (0.42) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL7915170 | 1.00 | TSHR (0.42) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL20528866 | 0.97 | TSHR (0.40) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL20528867 | 0.97 | TSHR (0.40) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL6016743 | 0.97 | — | — | |
| SCHEMBL28168681 | 0.95 | NAAA (0.36) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200718-B1 | A POLYMERIZED TONER OF CORE-SHELL STRUCTURE, COMPRISING CORE PARTICLES COMPOSED OF COLORED POLYMER PARTICLES WHICH CONTAIN A COMPOUND HAVING >C=N+ STRUCTURE IN ITS MOLECULE AND A COLORANT AND A LAYER OF POLYMER COVERING CORE PARTICLES | NIPPON ZEON CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| EP-0947888-A1 | POLYMER TONER AND METHOD OF PRODUCTION THEREOF | NIPPON ZEON CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |