SCHEMBL7915432

SCHEMBL7915432

Brc1c2ccccc2c(Br)c2ccccc12.[MgH2]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
ALDH1A1 P00352 8/20 0.41
TDP1 Q9NUW8 2/20 0.41
HSD17B10 Q99714 3/20 0.39
CYP2A6 P11509 2/20 0.39
TSHR P16473 1/20 0.39
GAA P10253 1/20 0.38
CYP1A2 P05177 4/20 0.37
IDO1 P14902 1/20 0.37
CYP2C19 P33261 2/20 0.36
GPR3 P46089 3/20 0.35
HPRT1 P00492 1/20 0.35
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28511 0.96 ALDH1A1 (0.44) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL29352635 0.96 ALDH1A1 (0.44) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL7240160 0.86 POLB (0.39) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL446563 0.86 POLB (0.39) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL5949863 0.85 POLB (0.42) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL29419982 0.85 HPRT1 (0.42) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL12627623 0.85 HPRT1 (0.42) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL30366469 0.85 POLB (0.42) POLBALDH1A1TDP1HSD17B10CYP2A6
Boric Acid SCHEMBL28173090 0.83 POLB (0.42) POLBALDH1A1TDP1HSD17B10CYP2A6
SCHEMBL23444303 0.81 KDM4E (0.46) POLBALDH1A1TDP1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-6277519-B1 QUENCHING AN ALLOY MELT; COMMINUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-21 US disclosed
EP-0872903-A1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder Shin-Etsu Chemical Co., Ltd. (JP) 1998-10-21 EP disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed