Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618325 | 0.89 | POLB (0.54) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL7274104 | 0.88 | CHRM2 (0.54) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL14001423 | 0.85 | CHRM2 (0.52) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL6253092 | 0.85 | CHRM2 (0.52) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9878913 | 0.85 | POLB (0.61) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| Temiverine SCHEMBL896437 | 0.84 | CHRM2 (0.70) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9878043 | 0.84 | MEN1 (0.53) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| Temiverine SCHEMBL120687 | 0.84 | CHRM2 (0.70) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9878732 | 0.84 | POLB (0.59) | POLBALDH1A1CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9878735 | 0.84 | HTT (0.59) | POLBALDH1A1CYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207852-B1 | THERAPY FOR INCONTINENCE; CROHN'S DISEASE; MUSCLE RELAXANTS | BRIDGE PHARMA, INC. | 2001-03-27 | — | — | US | disclosed |