Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15921910 | 0.86 | NFKB1 (0.75) | NFKB1BLMPMP22HIF1AEPAS1 | |
| SCHEMBL29633151 | 0.86 | NFKB1 (0.75) | NFKB1BLMPMP22HIF1AEPAS1 | |
| SCHEMBL7148550 | 0.86 | NFKB1 (0.75) | NFKB1BLMPMP22HIF1AEPAS1 | |
| SCHEMBL1966507 | 0.86 | NFKB1 (0.75) | NFKB1BLMPMP22HIF1AEPAS1 | |
| Hydrochloric Acid SCHEMBL8904803 | 0.84 | BLM (0.76) | NFKB1BLMPMP22HIF1AEPAS1 | |
| SCHEMBL6588285 | 0.82 | HIF1A (0.45) | NFKB1BLMPMP22HIF1AEPAS1 | |
| SCHEMBL30352690 | 0.81 | NFKB1 (0.60) | NFKB1BLMPMP22HIF1AEPAS1 | |
| SCHEMBL22713903 | 0.81 | NFKB1 (0.60) | NFKB1BLMPMP22HIF1AEPAS1 | |
| SCHEMBL7914446 | 0.81 | NFKB1 (0.60) | NFKB1BLMPMP22ADRA2AADRA1A | |
| SCHEMBL30352570 | 0.79 | PDE4B (0.63) | NFKB1BLMPMP22ADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265402-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0924204-A1 | 2-PHENYLMORPHOLIN-5-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-06-23 | — | — | EP | disclosed |