Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009738 | 1.00 | CA12 (0.39) | CA12CA1CA2CA4CA5A | |
| SCHEMBL14601945 | 0.88 | LGALS9 (0.37) | CA12CA1CA2CA4CA5A | |
| SCHEMBL17309270 | 0.85 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7905808 | 0.85 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL582508 | 0.85 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL13775041 | 0.85 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL14571449 | 0.85 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL19090190 | 0.85 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL18324625 | 0.85 | CA12 (0.49) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7455747 | 0.82 | CA12 (0.53) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274716-B1 | COMPRISE DISACCHARIDES AND TRISACCHARIDES COVALENTLY BONDED TO LIPID OR LIPID MIMETIC THROUGH PHOSPHOROUS LINKAGE; SCREENED FOR ANTI-MICROBIAL ACTIVITY BY CONTACTING THEM WITH CULTURE OF MICROBES AND MONITORING THE GROWTH RATE | ADVANCED MEDICINE, INC. | 2001-08-14 | — | — | US | disclosed |
| US-6207820-B1 | SOLID PHASE SYNTHESIS BY LINKING ACCEPTOR MONOSACCHARIDE TO SUPPORT FORMING CARBOXYLATE OR CARBOXYAMIDE LINKAGE, COVALENTLY LINKING DONOR SACCHARIDE BY O-GLYCOSIDIC LINKAGE, COUPLING LIPOPHOSPHOGLYCERATE MIMETIC, CLEAVING FROM SUPPORT | INCARA RESEARCH LABORATORIES | 2001-03-27 | — | — | US | disclosed |
| EP-1047703-A1 | A COMBINATORIAL LIBRARY OF MOENOMYCIN ANALOGS AND METHODS OF PRODUCING SAME | Incara Pharmaceutical Corp. (US) | 2000-11-02 | — | — | EP | disclosed |
| US-6114309-A | REACTION PRODUCT OF MONOSACCHARIDE, DISACCHARIDE AND LIPOPHOSPHOGLYCERATE MINETIC | INCARA RESEARCH LABORATORIES (US) | 2000-09-05 | — | — | US | disclosed |
| WO-1999026956-A1 | A COMBINATORIAL LIBRARY OF MOENOMYCIN ANALOGS AND METHODS OF PRODUCING SAME | INCARA PHARMACEUTICAL CORP. (US) | 1999-06-03 | — | — | WO | disclosed |