SCHEMBL7916083

SCHEMBL7916083

O=P(Oc1ccccc1Oc1ccc(Cl)cc1)(Oc1ccccc1Oc1ccc(Cl)cc1)Oc1ccccc1Oc1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
HTT P42858 4/20 0.46
HTR2A P28223 3/20 0.46
SLC6A4 P31645 3/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HPGD P15428 5/20 0.45
MAPT P10636 3/20 0.44
ALDH1A1 P00352 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 1/20 0.44
GAA P10253 1/20 0.42
ATM Q13315 1/20 0.42
PNLIP P16233 3/20 0.41
LMNA P02545 2/20 0.41
APEX1 P27695 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906266 0.84 LMNA (0.48) KMT2AHTTSLC6A4SLC6A2SLC6A3
SCHEMBL9462182 0.78 MEN1 (0.59) KMT2AMEN1HTTHPGDALDH1A1
SCHEMBL11548387 0.78 LMNA (0.43) KMT2AHTTSLC6A4SLC6A2SLC6A3
SCHEMBL9462195 0.78 LMNA (0.52) HTTHPGDALDH1A1L3MBTL1MAPK1
SCHEMBL11541949 0.76 HPGD (0.59) KMT2AMEN1HTTHPGDL3MBTL1
SCHEMBL11553341 0.76 HPGD (0.59) KMT2AMEN1HTTHPGDL3MBTL1
SCHEMBL1059937 0.75 MEN1 (0.67) KMT2AMEN1HTTHPGDALDH1A1
SCHEMBL2149766 0.75 HTR2A (0.53) KMT2AMEN1HTTHTR2ASLC6A4
SCHEMBL4314680 0.75 HTT (0.79) KMT2AMEN1HTTHTR2ASLC6A4
SCHEMBL9321769 0.74 HTR2A (0.53) KMT2AMEN1HTTHTR2ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218344-B1 WHICH CONSIST OF BASE FLUID HAVING LOW VOLATILITY AND A CHLORINATED TRIS(PHENOXYPHENYL)PHOSPHATE; EXTENDING USEFUL LIFE OF SATELLITES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2001-04-17 US disclosed