Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903030 | 0.83 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| SCHEMBL7902779 | 0.83 | KDM4E (0.73) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| SCHEMBL4791549 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| SCHEMBL4790870 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| SCHEMBL2899414 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| SCHEMBL7913070 | 0.81 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| Hydrochloric Acid SCHEMBL4791830 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| Hydrochloric Acid SCHEMBL3874412 | 0.81 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| SCHEMBL7913027 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG | |
| SCHEMBL2897233 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1SMN1; SMN2KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |