Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.69 |
| ▸ | MMP1 | P03956 | 14/20 | 0.69 |
| ▸ | MMP9 | P14780 | 10/20 | 0.69 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916943 | 1.00 | MMP2 (0.69) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7917022 | 0.92 | MMP2 (0.70) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7917019 | 0.92 | MMP2 (0.70) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7673809 | 0.82 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7677274 | 0.82 | MMP2 (0.83) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7452355 | 0.82 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7676418 | 0.81 | MMP2 (1.00) | MMP2MMP1MMP9 | |
| SCHEMBL7673801 | 0.81 | MMP2 (0.84) | MMP2MMP1MMP9 | |
| SCHEMBL7677435 | 0.80 | MMP2 (0.77) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7677270 | 0.80 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | claimed |
| US-6235786-B1 | RHEUMATIC DISORDERS; BONE DISORDERS; ORAL DISEASES; ANTIULCER AGENTS; ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-22 | — | — | US | disclosed |